Mouse Anti-Human MMP-3-HRP

Cat. No.
12020-05  
Size
1.0 mL  
Price (USD)
$315.00 
Clone SB14d
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-HRP
Immunogen Recombinant MMP-3
Specificity Human MMP-3
Alternalte Name(s) Matrix metalloproteinase 3, stomelysin-1, transin
Description Matrix metalloproteinases (MMPs) are a family of at least 23 structurally related, zinc-containing enzymes that have the ability to breakdown connective tissue. MMP-3 has shown substrate specificity to collagens types I, II, III, IV, VI, IX, X, and XIV as well as additional extracellular matrix components including gelatin, fibronectin, aggrecan, and perlecan.
Format/Conjugate HRP (Horseradish Peroxidase)
Buffer Formulation 50% Glycerol/50% Phosphate buffered saline, pH 7.4
Volume 1.0 mL
Storage & Handling 2-8°C
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
ELISA – Quality tested
Immunohistochemistry-Paraffin Sections 2
Immunohistochemistry-Frozen Sections – Reported in literature 1
Immunocytochemistry 3
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2794704
Gene ID
4314 (Human)
Gene Symbol
MMP3 (Human)
Gene Aliases CHDS6; MMP-3; SL-1; STMY; STMY1; STR1
Uniprot ID
P08254 (Human)
Uniprot Name
  • Paraffin embedded human kidney cancer tissue was stained with Mouse IgG2a-UNLB isotype control (SB Cat. No. 0103-01; left) and Mouse Anti-Human MMP-3-UNLB (SB Cat. No. 12020-01; right) followed by Goat Anti-Mouse IgG2a, Human ads-HRP (SB Cat. No. 1080-05), DAB, and hematoxylin.

Paraffin embedded human kidney cancer tissue was stained with Mouse IgG2a-UNLB isotype control (SB Cat. No. 0103-01; left) and Mouse Anti-Human MMP-3-UNLB (SB Cat. No. 12020-01; right) followed by Goat Anti-Mouse IgG2a, Human ads-HRP (SB Cat. No. 1080-05), DAB, and hematoxylin.
 
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References
1. Rijken F. Pathophysiology and prevention of photoaging : the role of melanin, reactive oxygen species and infiltrating neutrophils [dissertation]. Utrecht (Netherlands): Utrecht University; 2011. (IHC-FS)
2. SouthernBiotech published data (IHC-PS)
3. SouthernBiotech unpublished data (ICC)