Mouse Anti-Human Tollip-UNLB
Cat. No.
12060-01
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Size
0.1 mg
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Price (USD)
$310.00
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| Clone |
SB40a
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| Isotype |
Mouse (BALB/c) IgG2aκ
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| Isotype Control |
Mouse IgG2a-UNLB
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| Immunogen |
Recombinant full length Tollip
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| Specificity |
Human Tollip
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| Alternalte Name(s) |
Toll interacting protein, IL-1RAcPIP
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| Description |
Tollip, also known as Toll interacting protein, is a 30 kDa ubiquitin-binding protein that is a component of the signaling pathway of IL-1 and Toll-like receptors. It performs multiple functions and is classified as an adaptor protein. Tollip interacts with IRAK-1 (IL-1 receptor-associated kinase 1) prior to IL-1β stimulation and suppresses the kinase activity of IRAK-1. Tollip also associates with Tom1 forming a complex which regulates endosomal trafficking of ubiquitinated proteins.
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| Format/Conjugate |
UNLB (Unconjugated)
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| Buffer Formulation |
Borate buffered saline, pH 8.2
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| Concentration |
0.5 mg/mL
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| Volume |
0.2 mL
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| Storage & Handling |
2-8°C
Please refer to product specific SDS
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| Applications |
Applications for relevant formats of this clone include - Flow Cytometry – Quality tested 1
Western Blot 2
ELISA 2
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| Recommended Dilutions |
Please refer to product specific Technical Bulletin
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| RRID |
AB_2794709
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| Gene ID |
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| Gene Symbol |
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| Gene Aliases |
IL-1RAcPIP
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| Uniprot ID |
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| Uniprot Name |
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Human T cell leukemia cell line Jurkat was intracellularly stained with Mouse Anti-Human Tollip-UNLB (SB Cat. No. 12060-01) followed by Goat Anti-Mouse IgG2a, Human ads-PE (SB Cat. No. 1080-09).
Human T cell leukemia cell line Jurkat was intracellularly stained with Mouse Anti-Human Tollip-UNLB (SB Cat. No. 12060-01) followed by Goat Anti-Mouse IgG2a, Human ads-PE (SB Cat. No. 1080-09).
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References
| 1. | Blok DC, Kager LM, Hoogendijk AJ, Lede IO, Rahman W, Afroz R, et al. Expression of inhibitory regulators of innate immunity in patients with active tuberculosis. BMC Infect Dis. 2015;15:98. (FC) | | 2. | SouthernBiotech unpublished data (WB, ELISA) |
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