Mouse Anti-Human IL-18-UNLB

Cat. No.
15800-01  
Size
0.5 mg  
Price (USD)
$225.00 
Clone SB116c
Isotype Mouse (BALB/c) IgG3κ
Isotype Control Mouse IgG3-UNLB
Immunogen E. coli-expressed human IL-18
Specificity Human IL-18
Alternalte Name(s) Interleukin-18, IFN-gamma-inducing factor, IL-1 gamma
Description Interleukin-18 (IL-18), also known as IFN-gamma-inducing factor, is an 18 kDa protein and a member of the IL-1 family. This pro-inflammatory cytokine is primarily produced by antigen-presenting cells including monocytes/macrophages, as well as in keratinocytes and mucosal cell populations. Upon binding to target cells, IL-18 can induce natural killer (NK) cell activity, proliferation of activated T lymphocytes, and release of numerous pro-inflammatory cytokines. Moreover, this cytokine can promote Fas ligand expression in NK cells and enhance Fas ligand-mediated cytotoxicity of Th1 cells. Upregulation of IL-18 has been linked to several chronic inflammatory conditions including rheumatoid arthritis, heart disease and, atherosclerosis.
Format/Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Concentration 0.5 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
ELISA – Quality tested
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2794972
Gene ID
3606 (Human)
Gene Symbol
IL18 (Human)
Gene Aliases IGIF; IL-18; IL-1g; IL1F4
Uniprot ID
Q14116 (Human)
Uniprot Name
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