Mouse Anti-Human IL-21-UNLB

Cat. No.
15910-01  
Size
0.5 mg  
Price (USD)
$195.00 
Clone SB134f
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-UNLB
Immunogen E. coli-expressed human IL-21
Specificity Human IL-21
Alternalte Name(s) Interleukin-21, Za11
Description Interleukin-21 (IL-21) is a four helical bundle type I cytokine. The mature form of human IL-21 is a 131 amino acid protein. IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells, and augmentation of antitumor activity of CD8+ T cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
Format/Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Concentration 0.5 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
ELISA – Quality tested

Note – May be paired with the purified clone SB134b (SB Cat. No. 15900-01) in a sandwich ELISA
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2794997
Gene ID
59067 (Human)
Gene Symbol
IL21 (Human)
Gene Aliases CVID11; IL-21; Za11
Uniprot ID
Q9HBE4 (Human)
Uniprot Name
  • Serially diluted recombinant human IL-21 was captured with Mouse Anti-Human IL-21-UNLB (SB Cat. No. 15910-01). Human IL-21 was detected with Mouse Anti-Human IL-21 (SB Cat. No. 15900) conjugated to biotin followed by Streptavidin-HRP (SB Cat. No. 7100-05).

Serially diluted recombinant human IL-21 was captured with Mouse Anti-Human IL-21-UNLB (SB Cat. No. 15910-01). Human IL-21 was detected with Mouse Anti-Human IL-21 (SB Cat. No. 15900) conjugated to biotin followed by Streptavidin-HRP (SB Cat. No. 7100-05).
 
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