Mouse Anti-Human IL-21-UNLB
Cat. No.
15910-01
|
Size
0.5 mg
|
Price (USD)
$195.00
|
| Clone |
SB134f
|
| Isotype |
Mouse (BALB/c) IgG2aκ
|
| Isotype Control |
Mouse IgG2a-UNLB
|
| Immunogen |
E. coli-expressed human IL-21
|
| Specificity |
Human IL-21
|
| Alternalte Name(s) |
Interleukin-21, Za11
|
| Description |
Interleukin-21 (IL-21) is a four helical bundle type I cytokine. The mature form of human IL-21 is a 131 amino acid protein. IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells, and augmentation of antitumor activity of CD8+ T cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
|
| Format/Conjugate |
UNLB (Unconjugated)
|
| Buffer Formulation |
Borate buffered saline, pH 8.2
|
| Concentration |
0.5 mg/mL
|
| Volume |
1.0 mL
|
| Storage & Handling |
2-8°C
Please refer to product specific SDS
|
| Applications |
Applications for relevant formats of this clone include - ELISA – Quality tested
Note – May be paired with the purified clone SB134b (SB Cat. No. 15900-01) in a sandwich ELISA
|
| Recommended Dilutions |
Please refer to product specific Technical Bulletin
|
| RRID |
AB_2794997
|
| Gene ID |
|
| Gene Symbol |
|
| Gene Aliases |
CVID11; IL-21; Za11
|
| Uniprot ID |
|
| Uniprot Name |
|
|
|
-
Serially diluted recombinant human IL-21 was captured with Mouse Anti-Human IL-21-UNLB (SB Cat. No. 15910-01). Human IL-21 was detected with Mouse Anti-Human IL-21 (SB Cat. No. 15900) conjugated to biotin followed by Streptavidin-HRP (SB Cat. No. 7100-05).
Serially diluted recombinant human IL-21 was captured with Mouse Anti-Human IL-21-UNLB (SB Cat. No. 15910-01). Human IL-21 was detected with Mouse Anti-Human IL-21 (SB Cat. No. 15900) conjugated to biotin followed by Streptavidin-HRP (SB Cat. No. 7100-05).
|