Hamster Anti-Mouse CD79b-FITC

Cat. No.
1830-02  
Size
0.5 mg   		Price (USD)
$305.00 
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Clone HM79-12
Isotype Hamster (Armenian) IgG1
Isotype Control Hamster IgG-FITC
Immunogen CD79α/CD79β heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231
Specificity Mouse CD79b
Alternalte Name(s) B29, Igβ
Description Murine CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.
Format/Conjugate FITC (Fluorescein)
Buffer Formulation Phosphate buffered saline containing 0.1% sodium azide
Concentration 0.5 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C; Avoid exposure to light
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1-3
Immunoprecipitation – Reported in literature 1,2
Western Blot – Reported in literature 1
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2795405
Gene ID
15985 (Mouse)
Gene Symbol
Cd79b (Mouse)
Gene Aliases B29; Ig-beta; Igb; Igbeta
Uniprot ID
P15530 (Mouse)
Uniprot Name
CD79B_MOUSE 
  • Hamster Anti-Mouse CD79b-FITC
    BALB/c mouse splenocytes were stained with Hamster Anti-Mouse CD79b-FITC (SB Cat. No. 1830-02).

BALB/c mouse splenocytes were stained with Hamster Anti-Mouse CD79b-FITC (SB Cat. No. 1830-02).
 
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References
1. Koyama M, Ishihara K, Karasuyama H, Cordell JL, Iwamoto A, Nakamura T. CD79α/CD79β heterodimers are expressed on pro-B cell surfaces without associated μ heavy chain. Int Immunol. 1997;9:1767-72. (Immunogen, FC, IP, WB)
2. Kato I, Miyazaki T, Nakamura T, Kudo A. Inducible differentiation and apoptosis of the pre-B cell receptor-positive pre-B cell line. Int Immunol. 2000;12:325-34. (IP, FC)
3. McHeyzer-Williams LJ, Cool M, McHeyzer-Williams MG. Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment. J Exp Med. 2000;191:1149-65. (FC)