Hamster Anti-Mouse CD79b-FITC
Cat. No.
1830-02
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Size
0.5 mg
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Price (USD)
$305.00
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Clone |
HM79-12
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Isotype |
Hamster (Armenian) IgG1
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Isotype Control |
Hamster IgG-FITC
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Immunogen |
CD79α/CD79β heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231
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Specificity |
Mouse CD79b
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Alternalte Name(s) |
B29, Igβ
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Description |
Murine CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.
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Format/Conjugate |
FITC (Fluorescein)
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Buffer Formulation |
Phosphate buffered saline containing 0.1% sodium azide
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Concentration |
0.5 mg/mL
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Volume |
1.0 mL
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Storage & Handling |
2-8°C; Avoid exposure to light
Please refer to product specific SDS
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Applications |
Applications for relevant formats of this clone include - Flow Cytometry – Quality tested 1-3 Immunoprecipitation – Reported in literature 1,2 Western Blot – Reported in literature 1
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Recommended Dilutions |
Please refer to product specific Technical Bulletin
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RRID |
AB_2795405
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Gene ID |
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Gene Symbol |
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Gene Aliases |
B29; Ig-beta; Igb; Igbeta
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Uniprot ID |
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Uniprot Name |
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-
BALB/c mouse splenocytes were stained with Hamster Anti-Mouse CD79b-FITC (SB Cat. No. 1830-02).
BALB/c mouse splenocytes were stained with Hamster Anti-Mouse CD79b-FITC (SB Cat. No. 1830-02).
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References
1. | Koyama M, Ishihara K, Karasuyama H, Cordell JL, Iwamoto A, Nakamura T. CD79α/CD79β heterodimers are expressed on pro-B cell surfaces without associated μ heavy chain. Int Immunol. 1997;9:1767-72. (Immunogen, FC, IP, WB) | 2. | Kato I, Miyazaki T, Nakamura T, Kudo A. Inducible differentiation and apoptosis of the pre-B cell receptor-positive pre-B cell line. Int Immunol. 2000;12:325-34. (IP, FC) | 3. | McHeyzer-Williams LJ, Cool M, McHeyzer-Williams MG. Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment. J Exp Med. 2000;191:1149-65. (FC) |
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