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Mouse Anti-Mouse I-Ab-UNLB (25-9-3)
Cat. No.:
1896-01
Purified Anti-Mouse I-Ab antibody for use in flow cytometry, immunohistochemistry, and CMCD assays.
$246.00
| Clone | 25-9-3 |
|---|---|
| Isotype | Mouse (C3H) IgMκ |
| Isotype Control | Mouse IgM-UNLB (11E10) |
| Specificity | Mouse I-Ab |
| Alternative Names | MHC Class II |
| Description | The monoclonal antibody 25-9-3 reacts specifically with the I-Ab haplotype of MHC Class II molecules. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells. |
| Immunogen | C3H.SW mouse splenocytes |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications |
Flow Cytometry – Quality tested Immunohistochemistry-Frozen Sections – Reported in literature 2 Complement Mediated Cell Depletion – Reported in literature 3-6 |
| RRID Number | AB_2795449 |
| Gene ID |
14961 (Mouse) |
| Gene ID Symbol |
H2-Ab1 (Mouse) |
| Gene ID Aliases | AI845868; Abeta; H-2Ab; H2-Ab; I-Abeta; IAb; Ia-2; Ia2; Rmcs1 |
| UniProt ID |
P14483 (Mouse |
| UniProt Name |
HB2A_MOUSE (Mouse) |
Documentation
Certificate of Analysis Lookup
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- 1. Ozato K, Sachs DH. Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression. J Immunol. 1981;126:317-21. (Immunogen)
- 2. Komano H, Fujiura Y, Kawaguchi M, Matsumoto S, Hashimoto Y, Obana S, et al. Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells. Proc Natl Acad Sci USA. 1995;92:6147-51. (IHC-FS)
- 3. Sperling AI, Green JM, Mosley RL, Smith PL, DiPaolo RJ, Klein JR, et al. CD43 is a murine T cell costimulatory receptor that functions independently of CD28. J Exp Med. 1995;182:139-46. (CMDC)
- 4. Lenschow DJ, Sperling AI, Cooke MP, Freeman G, Rhee L, Decker DC, et al. Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen. J Immunol. 1994;153:1990-7. (CMDC)
- 5. Khattri R, Auger JA, Griffin MD, Sharpe AH, Bluestone JA. Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses. J Immunol. 1999;162:5784-91. (CMDC)
- 6. Rulifson IC, Szot GL, Palmer E, Bluestone JA. Inability to induce tolerance through direct antigen presentation. Am J Transplant. 2002;2:510-9. (CMDC)
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