Mouse Anti-Porcine CD1-UNLB

Cat. No.
4500-01  
Size
0.5 mg  
Price (USD)
$335.00 
Clone 76-7-4
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-UNLB
Immunogen Fresh dd miniature swine thymocytes
Specificity Porcine CD1
Alternalte Name(s) CD1c, CD1.1
Description Porcine CD1 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It has a domain organization similar to that of MHC class I molecules and is expressed in association with β2-microglobulin. CD1 is found on B cells, macrophages, and immature thymocytes. There is evidence for a role of CD1 in presentation of lipids and peptides to T cells.
Format/Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Concentration 0.5 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1,2,5,7-11
Immunohistochemistry-Frozen Sections – Reported in literature 2-6
Immunocytochemistry – Reported in literature 7
Immunoprecipitation – Reported in literature 1
Complement Mediated Cell Depletion – Reported in literature 1
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2796008
Gene ID
100124526 (Porcine)
Gene Symbol
CD1D (Porcine)
Gene Aliases CD1
  • Porcine peripheral blood lymphocytes were stained with Mouse Anti-Porcine CD1-UNLB (SB Cat. No. 4500-01) and Mouse Anti-Porcine CD3ε-PE (SB Cat. No. 4510-09) followed by Goat Anti-Mouse IgG2a, Human ads-FITC (SB Cat. No. 1080-02).

Porcine peripheral blood lymphocytes were stained with Mouse Anti-Porcine CD1-UNLB (SB Cat. No. 4500-01) and Mouse Anti-Porcine CD3ε-PE (SB Cat. No. 4510-09) followed by Goat Anti-Mouse IgG2a, Human ads-FITC (SB Cat. No. 1080-02).
 
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References
1. Pescovitz MD, Lunney JK, Sachs DH. Preparation and characterization of monoclonal antibodies reactive with porcine PBL. J Immunol. 1984;133:368-375. (Immunogen, FC, IP, CMDC)
2. Denham S, Zwart RJ, Whittall JT, Pampusch M, Corteyn AH, Bianchi AT, et al. Monoclonal antibodies putatively identifying porcine B cells. Vet Immunol Immunopathol. 1998;60:317-28. (IHC-FS, FC)
3. Pauly T, König M, Thiel H, Saalmüller A. Infection with classical swine fever virus: effects on phenotype and immune responsiveness of porcine T lymphocytes. J Gen Virol. 1998;79:31-40. (IHC-FS)
4. Yamada K, Shimizu A, Ierino FL, Utsugi R, Barth RN, Esnaola N, et al. Thymic transplantation in miniature swine. I. Development and function of the "thymokidney". Transplantation. 1999;68:1684-92. (IHC-FS)
5. Diaz-San Segundo F, Moraes MP, de Los Santos T, Dias CC, Grubman MJ. Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate immune cell infiltration and interferon-stimulated gene expression. J Virol. 2010;84:2063-77. (IHC-FS, FC)
6. Debeer S, Le Luduec J, Kaiserlian D, Laurent P, Nicolas JF, Dubois B, et al. Comparative histology and immunohistochemistry of porcine versus human skin. Eur J Dermatol. 2013;23:456-66. (IHC-FS)
7. Nfon CK, Dawson H, Toka FN, Golde WT. Langerhans cells in porcine skin. Vet Immunol Immunopathol. 2008;126:236-47. (ICC, FC)
8. Layton DS, Bean AG, Dodge NM, Strom AD, Sandrin MS, Ierino FL. Differential cytokine expression and regulation of human anti-pig xenogeneic responses by modified porcine dendritic cells. Xenotransplantation. 2008;15:257-67. (FC)
9. Facci MR, Auray G, Buchanan R, van Kessel J, Thompson DR, Mackenzie-Dyck S, et al. A comparison between isolated blood dendritic cells and monocyte-derived dendritic cells in pigs. Immunology. 2010;129:396-405. (FC)
10. Chen L, Dong X, Shen H, Zhao M, Ju C, Yi L, et al. Classical swine fever virus suppresses maturation and modulates functions of monocyte-derived dendritic cells without activating nuclear factor kappa B. Res Vet Sci. 2012;93:529-37. (FC)
11. Leclercq C, Prunier A, Thomas F, Merlot E. Neonatal surgical castration of male pigs reduces thymic growth but has moderate consequences on thymocytes. J Anim Sci. 2014;92:2415-21. (FC)