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Mouse Anti-Human Caspase-3-HRP (SB71b)

Cat. No.:
HRP Anti-Human Caspase-3 antibody for use in western blot assays.
Size Price (USD) Quantity
1.0 mL $193.00
More Information
Clone SB71b
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-HRP (HOPC-1)
Specificity Human caspase-3
Alternative Names SPP32, Yama, apopain
Description The caspases are a family of cysteine proteases that induce apoptosis in response to a variety of intra- and extracellular stimuli. These enzymes are synthesized as inactive precursors which become cleaved at aspartate-specific sites upon induction of apoptosis. Caspase-3 is one of the best characterized caspases in terms of specificity and function in apoptosis. It is a ubiquitously expressed protein in mammals and is highly prevalent in cells with lymphocytic origins, indicating a regulatory role in the immune system. Caspase-3 plays a critical role during embryonic development by inducing morphogenetic cell death in the mammalian brain and has also been linked to chromatin condensation, DNA fragmentation, and blebbing.

The SB71b monoclonal antibody detects endogenous levels of full length caspase-3 (35 kDa) and the large fragment of caspase-3 resulting from cleavage (17 kDa).
Immunogen Recombinant human caspase-3
Conjugate HRP (Horseradish Peroxidase)
Buffer Formulation 50% Glycerol/50% Phosphate buffered saline, pH 7.4
Clonality Monoclonal
Concentration Lot specific
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Western Blot – Quality tested

RRID Number AB_2795189
Gene ID 836 (Human)
Gene ID Symbol CASP3 (Human)
Gene ID Aliases CPP32; CPP32B; SCA-1
UniProt ID P42574 (Human)
UniProt Name CASP3_HUMAN (Human)

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