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Goat F(ab')2 Anti-Human IgD-PE

Cat. No.:
2032-09
Goat F(ab')2 Anti-Human IgD-PE antibody for use in flow cytometry assays.
$270.00
Size Price (USD) Quantity
0.25 mg $270.00
More Information
Isotype Goat F(ab')2 IgG
Isotype Control Goat F(ab')2 IgG-PE
Specificity Reacts with the heavy chain of human IgD
Source Pepsin digest of Goat Anti-Human IgD (SB Cat. No. 2030)
Cross Adsorption Human IgG, IgM, and IgA; may react with IgD from other species
Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Clonality Polyclonal
Concentration 0.25 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light; Do not freeze
Applications Quality tested applications for relevant formats include -
ELISA
FLISA
Flow Cytometry 3-5,7-11

Other referenced applications for relevant formats include -
Immunohistochemistry-Frozen Sections 1-3,6,9
Immunohistochemistry-Paraffin Sections 3
Separation 1,6
Stimulation 12-14
RRID Number AB_2795636
Gene ID 3495 (Human)
Gene ID Symbol IGHD (Human)
UniProt ID P01880 (Human)
UniProt Name IGHD_HUMAN (Human)

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  1. 1. Xu W, He B, Chiu A, Chadburn A, Shan M, Buldys M, et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat Immunol. 2007;8:294-303. (IHC-FS, Sep)
  2. 2. Xu W, Santini PA, Matthews AJ, Chiu A, Plebani A, He B, et al. Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. J Immunol. 2008;181:276-87. (IHC-FS)
  3. 3. Chen K, Xu W, Wilson M, He B, Miller NW, Bengtén E, et al. Immunoglobulin D enhances immune surveillance by activating antimicrobial, pro-inflammatory and B cell-stimulating programs in basophils. Nat Immunol. 2009;10:889-98. (IHC-FS, IHC-PS, FC)
  4. 4. Green LL, Jakobovits A. Regulation of B cell development by variable gene complexity in mice reconstituted with human immunoglobulin yeast artificial chromosomes. J Exp Med. 1998;188:483-95. (FC)
  5. 5. Joseph AM, Babcock GJ, Thorley-Lawson DA. EBV persistence involves strict selection of latently infected B cells. J Immunol. 2000;165:2975-81. (FC)
  6. 6. He B, Xu W, Santini PA, Polydorides AD, Chiu A, Estrella J, et al. Intestinal bacteria trigger T cell-independent immunoglobulin A2 class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity. 2007;26:812-26. (Sep, IHC-FS)
  7. 7. Warnatz K, Schlesier M. Flowcytometric phenotyping of common variable immunodeficiency. Cytometry B Clin Cytom. 2008;74:261-71. (FC)
  8. 8. He B, Santamaria R, Xu W, Cols M, Chen K, Puga I, et al. The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat Immunol. 2010;11:836-45. (FC)
  9. 9. Puga I, Cols M, Barra CM, He B, Cassis L, Gentile M, et al. B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nat Immunol. 2012;13:170-80. (FC, IHC-FS)
  10. 10. Gieseke F, Mang P, Viebahn S, Sonntag I, Kruchen A, Erbacher A, et al. Siglec-7 tetramers characterize B-cell subpopulations and leukemic blasts. Eur J Immunol. 2012;42:2176-86. (FC)
  11. 11. Li FJ, Schreeder DM, Li R, Wu J, Davis RS. FCRL3 promotes TLR9-induced B-cell activation and suppresses plasma cell differentiation. Eur J Immunol. 2013;43:2980-92. (FC)
  12. 12. Jiang A, Clark EA. Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis. J Immunol. 2001;166:6025-33. (Stim)
  13. 13. Rankin AL, Seth N, Keegan S, Andreyeva T, Cook TA, Edmonds J, et al. Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis. J Immunol. 2013;191:4540-50. (Stim)
  14. 14. Smith MJ, Packard TA, O'Neill SK, Dunand CJ, Huang M, Fitzgerald-Miller L, et al. Loss of anergic B cells in pre-diabetic and new onset T1D patients. Diabetes. 2014 Dec 18. pii: DB_131798. [Epub ahead of print]. (Stim)
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