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Rabbit Anti-Human DR5-UNLB
Cat. No.:
6600-01
Purified Anti-Human DR5 antibody for use in flow cytometry, immunocytochemistry, and western blot assays.
$259.00
| Isotype | Rabbit IgG |
|---|---|
| Isotype Control | Rabbit IgG-UNLB |
| Specificity | Human DR5 |
| Alternative Names | CD262, TRAIL-R2, KILLER, TRICK2, TNFRSF10B, Ly98 |
| Description | DR5, also known as TRAIL-R2, TRICK2 and KILLER, is a widely expressed type I membrane member of the tumor necrosis (TNF) receptor family. Members of this family contain multiple cysteine-rich repeats in their extracellular domain and while the cytoplasmic region is less conserved, they do contain an intracellular 80 amino acid motif known as the ‘death domain’ (DD). DR5 is a receptor for the cytotoxic ligand TRAIL which induces apoptosis and it is the cytoplasmic DD that is responsible for transducing the death process. DR5 has also been shown to activate NF-κB. |
| Immunogen | Recombinant DR5 |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/mL |
| Volume | 0.2 mL |
| Recommended Storage | 2-8°C |
| Applications |
Quality tested applications for relevant formats include - Flow Cytometry – Quality tested Western Blot 1 Immunocytochemistry 1 |
| RRID Number | AB_2796399 |
| Gene ID |
8795 (Human) |
| Gene ID Symbol |
TNFRSF10B (Human) |
| Gene ID Aliases | CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 |
| UniProt ID |
O14763 (Human) |
| UniProt Name |
TR10B_HUMAN (Human) |
Documentation
Certificate of Analysis Lookup
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- 1. SouthernBiotech published data (WB, ICC)
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