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Rabbit Anti-Human DR5-UNLB

Cat. No.:
6600-01
Purified Anti-Human DR5 antibody for use in flow cytometry, immunocytochemistry, and western blot assays.
$259.00
Size Price (USD) Quantity
0.1 mg $259.00
More Information
Isotype Rabbit IgG
Isotype Control Rabbit IgG-UNLB
Specificity Human DR5
Alternative Names CD262, TRAIL-R2, KILLER, TRICK2, TNFRSF10B, Ly98
Description DR5, also known as TRAIL-R2, TRICK2 and KILLER, is a widely expressed type I membrane member of the tumor necrosis (TNF) receptor family. Members of this family contain multiple cysteine-rich repeats in their extracellular domain and while the cytoplasmic region is less conserved, they do contain an intracellular 80 amino acid motif known as the ‘death domain’ (DD). DR5 is a receptor for the cytotoxic ligand TRAIL which induces apoptosis and it is the cytoplasmic DD that is responsible for transducing the death process. DR5 has also been shown to activate NF-κB.
Immunogen Recombinant DR5
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Polyclonal
Concentration 0.5 mg/mL
Volume 0.2 mL
Recommended Storage 2-8°C
Applications Quality tested applications for relevant formats include -
Flow Cytometry – Quality tested
Western Blot 1
Immunocytochemistry 1

RRID Number AB_2796399
Gene ID 8795 (Human)
Gene ID Symbol TNFRSF10B (Human)
Gene ID Aliases CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
UniProt ID O14763 (Human
UniProt Name TR10B_HUMAN (Human)

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  1. 1. SouthernBiotech published data (WB, ICC)