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Rat Anti-Mouse CD102-LE/AF (3C4)

Cat. No.:
Low Endotoxin/Azide Free Anti-Mouse CD102 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
Size Price (USD) Quantity
0.5 mg $385.00
More Information
Clone 3C4
Isotype Rat (Lewis) IgG2aκ
Isotype Control Rat IgG2a-LE/AF (KLH/G2a-1-1)
Specificity Mouse CD102
Alternative Names ICAM-2, intercellular adhesion molecule-2
Description The 3C4 monoclonal antibody reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1.
Immunogen COS cells transfected with mouse ICAM-2 cDNA and BW5147 AKR/J mouse thymoma cell line
Conjugate LE/AF (Low Endotoxin/Azide Free)
Buffer Formulation Phosphate buffered saline, pH 7.4
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Handle under aseptic conditions
Applications Flow Cytometry – Quality tested 1,5
Immunohistochemistry-Frozen Sections – Reported in literature 2,3
Immunocytochemistry – Reported in literature 4,5
Immunoprecipitation – Reported in literature 1
Blocking – Reported in literature 1

RRID Number AB_2795543
Gene ID 15896 (Mouse)
Gene ID Symbol Icam2 (Mouse)
Gene ID Aliases CD102; Icam-2; Ly-60
UniProt ID P35330 (Mouse)
UniProt Name ICAM2_MOUSE (Mouse)

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  1. 1. Xu H, Bickford JK, Luther E, Carpenito C, Takei F, Springer TA. Characterization of murine intercellular adhesion molecule-2. J Immunol. 1996;156:4909-14. (Immunogen, FC, IP, Block)
  2. 2. Cao G, Savani RC, Fehrenbach M, Lyons C, Zhang L, Coukos G, et al. Involvement of endothelial CD44 during in vivo angiogenesis. Am J Pathol. 2006;169:325-36. (IHC-FS)
  3. 3. Cao G, Fehrenbach ML, Williams JT, Finklestein JM, Zhu J, DeLisser HM. Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice. Am J Pathol. 2009;175:903-15. (IHC-FS)
  4. 4. Shin J, Lee JC, Baek K. A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis. Cancer Lett. 2014;342:70-81. (ICC)
  5. 5. Fehrenbach ML, Cao G, Williams JT, Finklestein JM, DeLisser HM. Isolation of murine lung endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2009;296:L1096-1103. (ICC, FC)
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