Ensuring timely antibody delivery in the face of supply chain challenges - contact us for solutions

Rat Anti-Mouse CD18-LE/AF (C71/16)

Cat. No.:
Low Endotoxin/Azide Free Anti-Mouse CD18 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blot, and immunoprecipitation assays.
Size Price (USD) Quantity
0.5 mg $270.00
More Information
Clone C71/16
Isotype Rat (Lewis) IgG2aκ
Isotype Control Rat IgG2a-LE/AF (KLH/G2a-1-1)
Specificity Mouse CD18
Alternative Names Integrin β2, ITGB2
Description CD18 represents the common β2 integrin subunit that associates non-covalently with the α/β chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic intercellular adhesion reactions and it regulates the ligand-binding activates of the various CD11/CD18 complexes. The monoclonal antibody C71/16 has not been reported to inhibit cell adhesion.
Immunogen Cell membrane glycoproteins derived from mouse BW5147 T cell lymphoma cells
Conjugate LE/AF (Low Endotoxin/Azide Free)
Buffer Formulation Phosphate buffered saline, pH 7.4
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Handle under aseptic conditions
Applications Flow Cytometry – Quality tested 2
Immunohistochemistry-Frozen Sections – Reported in literature 3
Immunohistochemistry-Paraffin Sections – Reported in literature 4
Immunocytochemistry – Reported in literature 2
Immunoprecipitation – Reported in literature 1,2
Western Blot – Reported in literature 2
ELISA – Reported in literature 5

RRID Number AB_2794944
Gene ID 16414 (Mouse)
Gene ID Symbol Itgb2 (Mouse)
Gene ID Aliases 2E6; LAD; Cd18; Lfa1; MF17; LCAMB; AI528527
UniProt ID P11835 (Mouse
UniProt Name ITB2_MOUSE (Mouse)

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view

Need help with this product?
or call 800.722.2255
  1. 1. Trowbridge IS, Omary MB. Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. J Exp Med. 1981;154:1517-24. (Immunogen, IP)
  2. 2. Choi EY, Orlova VV, Fagerholm SC, Nurmi SM, Chang L, Ballantyne CM, et al. Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins. Blood. 2008;111:3607-14. (IP, WB, ICC, FC)
  3. 3. Bullard DC, Scharffetter-Kochanek K, McArthur MJ, Chosay JG, McBride ME, Montgomery CA, et al. A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice. Proc Natl Acad Sci USA. 1996;93:2116-21. (IHC-FS)
  4. 4. Gerth AJ, Lin L, Neurath MF, Glimcher LH, Peng SL. An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells. Gastroenterology. 2004;126:1115-21. (IHC-PS)
  5. 5. Shirakabe K, Shibagaki Y, Yoshimura A, Koyasu S, Hattori S. A proteomic approach for the elucidation of the specificity of ectodomain shedding. J Proteomics. 2014;98:233-43. (ELISA)
See All References