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Rat Anti-Mouse CD18-UNLB (C71/16)

Cat. No:
1570-01
Purified Anti-Mouse CD18 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blot, and immunoprecipitation assays.
$192.00
Size Price (USD) Quantity
0.5 mg $192.00
More Information
Clone C71/16
Isotype Rat (Lewis) IgG2aκ
Isotype Control Rat IgG2a-UNLB (KLH/G2a-1-1)
Specificity Mouse CD18
Alternative Names Integrin β2, ITGB2
Description CD18 represents the common β2 integrin subunit that associates non-covalently with the α/β chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic intercellular adhesion reactions and it regulates the ligand-binding activates of the various CD11/CD18 complexes. The monoclonal antibody C71/16 has not been reported to inhibit cell adhesion.
Immunogen Cell membrane glycoproteins derived from mouse BW5147 T cell lymphoma cells
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Flow Cytometry – Quality tested 2
Immunohistochemistry-Frozen Sections – Reported in literature 3
Immunohistochemistry-Paraffin Sections – Reported in literature 4
Immunocytochemistry – Reported in literature 2
Immunoprecipitation – Reported in literature 1,2
Western Blot – Reported in literature 2
ELISA – Reported in literature 5

RRID Number AB_2794940
Gene ID 16414 (Mouse)
Gene ID Symbol Itgb2 (Mouse)
Gene ID Aliases 2E6; LAD; Cd18; Lfa1; MF17; LCAMB; AI528527
UniProt ID P11835 (Mouse)
UniProt Name ITB2_MOUSE (Mouse)

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  1. 1. Trowbridge IS, Omary MB. Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. J Exp Med. 1981;154:1517-24. (Immunogen, IP)
  2. 2. Choi EY, Orlova VV, Fagerholm SC, Nurmi SM, Chang L, Ballantyne CM, et al. Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins. Blood. 2008;111:3607-14. (IP, WB, ICC, FC)
  3. 3. Bullard DC, Scharffetter-Kochanek K, McArthur MJ, Chosay JG, McBride ME, Montgomery CA, et al. A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice. Proc Natl Acad Sci USA. 1996;93:2116-21. (IHC-FS)
  4. 4. Gerth AJ, Lin L, Neurath MF, Glimcher LH, Peng SL. An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells. Gastroenterology. 2004;126:1115-21. (IHC-PS)
  5. 5. Shirakabe K, Shibagaki Y, Yoshimura A, Koyasu S, Hattori S. A proteomic approach for the elucidation of the specificity of ectodomain shedding. J Proteomics. 2014;98:233-43. (ELISA)
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