Rat Anti-Mouse CD24-SPRD (30-F1)
PE/CY5 (SPRD) Anti-Mouse CD24 antibody for use in flow cytometry assays.
|Isotype||Rat (LOU/Ws1/M) IgG2cκ|
|Alternative Names||Heat stable antigen, HSA|
|Description||CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory molecule. The CD24 molecule, also known as HSA, is composed mostly of carbohydrate with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property suggesting that the molecule is capable of promoting homotypic aggregation, binding, and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with an anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24 as a ligand for P-selectin, a calcium-dependent lectin.|
|Immunogen||Mouse thymus or spleen|
|Conjugate||SPRD (R-phycoerythrin/Cyanine 5)|
|Buffer Formulation||Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer|
|Recommended Storage||2-8°C; Avoid exposure to light; Do not freeze|
Spectral Red® is a registered trademark of Southern Biotechnology Associates, Inc.
Spectral Red® is a PE/CY5 tandem conjugate
Cy® is a registered trademark of Global Life Sciences Solutions Germany GmbH
Flow Cytometry – Quality tested 1-4|
|Gene ID Symbol||
|Gene ID Aliases||HSA; Cd24; Ly-52; nectadrin|
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