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Rat Anti-Mouse CD5-PE (4H8E5)

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Cat. No.:
PE Anti-Mouse CD5 antibody for use in flow cytometry assays.
As low as $176.00
Size Price (USD) Quantity
0.2 mg (Cat. No. 1546-09L) $286.00
0.1 mg (Cat. No. 1546-09) $176.00
More Information
Clone 4H8E5
Isotype Rat IgG2aκ
Isotype Control Rat IgG2a-PE (KLH/G2a-1-1)
Specificity Mouse CD5
Alternative Names Lyt-1, Ly-1, Lymphocyte antigen 1, Ly-12, Ly-A, T1, Tp67
Description CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL or 2.0 mL
Recommended Storage 2-8°C; Avoid exposure to light; Do not freeze
Applications Flow Cytometry – Quality tested 1

RRID Number AB_2794859
Gene ID 12507 (Mouse)
Gene ID Symbol Cd5 (Mouse)
Gene ID Aliases Ly-1; Ly-12; Ly-A; Lyt-1
UniProt ID P13379 (Mouse
UniProt Name CD5_MOUSE (Mouse)

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  1. 1. Koneru M, Schaer D, Monu N, Ayala A, Frey AB. Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function. J Immunol. 2005;174:1830-40. (FC)