Rat Anti-Mouse CD102-Pacific Blue™

Cat. No.
1925-26  
Size
0.1 mg  
Price (USD)
$190.00 
Clone 3C4
Isotype Rat (Lewis) IgG2aκ
Isotype Control Rat IgG2a-Pacific Blue™
Immunogen COS cells transfected with mouse ICAM-2 cDNA and BW5147 AKR/J mouse thymoma cell line
Specificity Mouse CD102
Alternalte Name(s) ICAM-2, intercellular adhesion molecule-2
Description The 3C4 monoclonal antibody reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1.
Format/Conjugate PACBLU (Pacific Blue™)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Concentration 0.5 mg/mL
Volume 0.2 mL
Storage & Handling 2-8°C; Avoid exposure to light
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1,5
Immunohistochemistry-Frozen Sections – Reported in literature 2,3
Immunocytochemistry – Reported in literature 4,5
Immunoprecipitation – Reported in literature 1
Blocking – Reported in literature 1
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2795544
Gene ID
15896 (Mouse)
Gene Symbol
Icam2 (Mouse)
Gene Aliases CD102; Icam-2; Ly-60
Uniprot ID
P35330 (Mouse)
Uniprot Name
  • BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD102-PACBLU (SB Cat. No. 1925-26).

BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD102-PACBLU (SB Cat. No. 1925-26).
 
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References
1. Xu H, Bickford JK, Luther E, Carpenito C, Takei F, Springer TA. Characterization of murine intercellular adhesion molecule-2. J Immunol. 1996;156:4909-14. (Immunogen, FC, IP, Block)
2. Cao G, Savani RC, Fehrenbach M, Lyons C, Zhang L, Coukos G, et al. Involvement of endothelial CD44 during in vivo angiogenesis. Am J Pathol. 2006;169:325-36. (IHC-FS)
3. Cao G, Fehrenbach ML, Williams JT, Finklestein JM, Zhu J, DeLisser HM. Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice. Am J Pathol. 2009;175:903-15. (IHC-FS)
4. Shin J, Lee JC, Baek K. A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis. Cancer Lett. 2014;342:70-81. (ICC)
5. Fehrenbach ML, Cao G, Williams JT, Finklestein JM, DeLisser HM. Isolation of murine lung endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2009;296:L1096-1103. (ICC, FC)
Pacific Blue™ is a trademark of Life Technologies Corporation