Rat Anti-Mouse CD24-BIOT (91)
Biotin Anti-Mouse CD24 antibody for use in flow cytometry and immunohistochemistry assays.
|Isotype Control||Rat IgG2a-BIOT (KLH/G2a-1-1)|
|Alternative Names||Heat stable antigen, HSA|
|Description||CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.|
|Buffer Formulation||Phosphate buffered saline containing < 0.1% sodium azide|
Flow Cytometry – Quality tested 2|
Immunohistochemistry-Frozen Sections – Reported in literature 1
|Gene ID Symbol||
|Gene ID Aliases||HSA; Cd24; Ly-52; nectadrin|
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- 1. Frings PW, Van Elssen CH, Wieten L, Matos C, Hupperets PS, Schouten HC, et al. Elimination of the chemotherapy resistant subpopulation of 4T1 mouse breast cancer by haploidentical NK cells cures the vast majority of mice. Breast Cancer Res Treat. 2011;130:773-81. (IHC-FS)
- 2. Zhou X, Bailey-Bucktrout S, Jeker LT, Penaranda C, Martinez-Llordella M, Ashby M, et al. Foxp3 instability leads to the generation of pathogenic memory T cells in vivo. Nat Immunol. 2009;10:1000-7. (FC)