Rat Anti-Mouse CD24-APC

Cat. No.
1590-11  
Size
0.1 mg   		Price (USD)
$245.00 
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Clone 91
Isotype Rat IgG2aκ
Isotype Control Rat IgG2a-APC
Specificity Mouse CD24
Alternalte Name(s) Heat stable antigen, HSA
Description CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.
Format/Conjugate APC (Allophycocyanin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Concentration 0.1 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C; Avoid exposure to light; Do not freeze
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 2
Immunohistochemistry-Frozen Sections – Reported in literature 1
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2794994
Gene ID
12484 (Mouse)
Gene Symbol
Cd24a (Mouse)
Gene Aliases HSA; Cd24; Ly-52; nectadrin
Uniprot ID
P24807 (Mouse)
Uniprot Name
CD24_MOUSE 
  • Rat Anti-Mouse CD24-APC
    BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD24-APC (SB Cat. No. 1590-11) and Rat Anti-Mouse CD3ε-FITC (SB Cat. No. 1535-02).

BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD24-APC (SB Cat. No. 1590-11) and Rat Anti-Mouse CD3ε-FITC (SB Cat. No. 1535-02).
 
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References
1. Frings PW, Van Elssen CH, Wieten L, Matos C, Hupperets PS, Schouten HC, et al. Elimination of the chemotherapy resistant subpopulation of 4T1 mouse breast cancer by haploidentical NK cells cures the vast majority of mice. Breast Cancer Res Treat. 2011;130:773-81. (IHC-FS)
2. Zhou X, Bailey-Bucktrout S, Jeker LT, Penaranda C, Martinez-Llordella M, Ashby M, et al. Foxp3 instability leads to the generation of pathogenic memory T cells in vivo. Nat Immunol. 2009;10:1000-7. (FC)